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How Can Microbial Infections Trigger Autoimmune Responses?

Microbial infections can sometimes trigger autoimmune responses in our bodies. Here’s how this can happen:

  1. Molecular Mimicry: Some germs have tiny parts, called antigens, that look a lot like our own body tissues. This confuses our immune system. For example, the streptococcus bacteria can resemble heart tissue, which might lead to a condition called rheumatic fever.

  2. Bystander Activation: When we get an infection, it can make our immune system go into overdrive. This might mistakenly make it attack healthy tissues, thinking they're harmful.

  3. Superantigens: Certain bacteria can release special substances that get many T-cells (a type of immune cell) active all at once. This can cause a lot of inflammation and lead to autoimmune issues.

These points show how our immune system has a tough job. It needs to protect us from germs, but sometimes it can accidentally turn against our own body. It's a fascinating yet complicated topic!

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Bacteriology for Medical MicrobiologyVirology for Medical MicrobiologyImmunology for Medical Microbiology
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How Can Microbial Infections Trigger Autoimmune Responses?

Microbial infections can sometimes trigger autoimmune responses in our bodies. Here’s how this can happen:

  1. Molecular Mimicry: Some germs have tiny parts, called antigens, that look a lot like our own body tissues. This confuses our immune system. For example, the streptococcus bacteria can resemble heart tissue, which might lead to a condition called rheumatic fever.

  2. Bystander Activation: When we get an infection, it can make our immune system go into overdrive. This might mistakenly make it attack healthy tissues, thinking they're harmful.

  3. Superantigens: Certain bacteria can release special substances that get many T-cells (a type of immune cell) active all at once. This can cause a lot of inflammation and lead to autoimmune issues.

These points show how our immune system has a tough job. It needs to protect us from germs, but sometimes it can accidentally turn against our own body. It's a fascinating yet complicated topic!

Related articles