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How Do Age-Related Changes Impact Drug Metabolism in the Elderly?

As people get older, their bodies change in ways that affect how they process medications. There are a few important reasons for this:

  • Liver Changes: The liver, which helps break down drugs, can shrink and receive less blood. This means it takes longer for many medications to be processed.

  • Kidney Changes: The kidneys might not work as well as they used to. This can cause drugs to stay in the body longer, which might lead to a need for lower doses.

  • Body Changes: As people age, they often have more body fat and less muscle. This can change how medications are stored in the body.

Because of these changes, older adults might be at a higher risk for side effects or bad reactions to medications. It's important for doctors to consider these factors when prescribing drugs to older patients.

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How Do Age-Related Changes Impact Drug Metabolism in the Elderly?

As people get older, their bodies change in ways that affect how they process medications. There are a few important reasons for this:

  • Liver Changes: The liver, which helps break down drugs, can shrink and receive less blood. This means it takes longer for many medications to be processed.

  • Kidney Changes: The kidneys might not work as well as they used to. This can cause drugs to stay in the body longer, which might lead to a need for lower doses.

  • Body Changes: As people age, they often have more body fat and less muscle. This can change how medications are stored in the body.

Because of these changes, older adults might be at a higher risk for side effects or bad reactions to medications. It's important for doctors to consider these factors when prescribing drugs to older patients.

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