Neurodegenerative diseases change how we move. They do this by causing the brain to lose special cells called neurons. These diseases affect different parts of the brain and can make it hard to control our bodies. Let's look at a few types of these diseases and how they affect movement.

1. Parkinson's Disease:

   • People with Parkinson’s often have shaking hands, stiff muscles, and slow movements.
   • This happens because neurons that help control movement in a brain area called the substantia nigra start to disappear.

2. Amyotrophic Lateral Sclerosis (ALS):

   • ALS affects motor neurons, which are important for moving muscles.
   • This can make muscles weak and lead to problems with simple tasks like walking or talking as time goes on.

3. Multiple Sclerosis (MS):

   • In MS, the protective covering around neurons gets damaged.
   • This can cause problems with sending signals in the brain. People might have muscle spasms, feel weak, or have trouble with coordination.

4. Huntington's Disease:

   • This disease leads to jerky and uncontrolled movements due to neuron damage in the basal ganglia.
   • As a result, it becomes hard to make intentional movements or keep things balanced.

In conclusion, these diseases can greatly impact how we move every day. They show us just how important the brain is for moving and coordinating our bodies.