Drug interactions can have a big effect on how well a treatment works and how safe it is for patients. Here are some important points to know:

1. Pharmacokinetic Interactions:

   • These are changes in how a drug is absorbed, spread around the body, broken down, or removed.
   • For example, some drugs can make other drugs build up in the body by as much as 100%.

2. Pharmacodynamic Interactions:

   • This is when two drugs affect each other’s actions on the body.
   • About 40% of negative reactions to drugs happen because of this.

3. Clinical Implications:

   • Roughly 30% of patients in hospitals deal with drug-drug interactions.
   • Almost 50% of these interactions can cause serious health problems, which is why it’s important to regularly check patients' medications.

Knowing about these drug interactions is essential. It helps make treatments better and keeps patients safe from harmful effects.