Impaired autophagy and lysosomal function are important factors in brain cell damage. Let’s break down how this happens:
Waste Buildup: When autophagy isn’t working properly, damaged proteins and parts of cells pile up. This can cause stress in the cells and make it harder for neurons (brain cells) to function.
Lysosomal Problems: Lysosomes help break down waste in cells. If they aren’t working well, harmful substances aren’t removed effectively, which can lead to more brain cell death.
Brain Inflammation: When toxic waste builds up, it can trigger inflammation. This makes the situation worse for brain health and can speed up disease.
Link to Diseases: This broken recycling process is connected to several serious brain diseases, like Alzheimer’s and Parkinson’s. In these diseases, communication in the brain gets messed up, and the health of the cells decreases.
In short, keeping autophagy and lysosomal function working properly is very important for keeping brain cells alive and healthy.
Impaired autophagy and lysosomal function are important factors in brain cell damage. Let’s break down how this happens:
Waste Buildup: When autophagy isn’t working properly, damaged proteins and parts of cells pile up. This can cause stress in the cells and make it harder for neurons (brain cells) to function.
Lysosomal Problems: Lysosomes help break down waste in cells. If they aren’t working well, harmful substances aren’t removed effectively, which can lead to more brain cell death.
Brain Inflammation: When toxic waste builds up, it can trigger inflammation. This makes the situation worse for brain health and can speed up disease.
Link to Diseases: This broken recycling process is connected to several serious brain diseases, like Alzheimer’s and Parkinson’s. In these diseases, communication in the brain gets messed up, and the health of the cells decreases.
In short, keeping autophagy and lysosomal function working properly is very important for keeping brain cells alive and healthy.