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How Do Insulin and Glucagon Orchestrate Energy Homeostasis?

Insulin and glucagon are two important hormones that help keep our energy levels balanced.

  1. What Insulin Does:

    • Insulin is made by special cells in the pancreas when blood sugar (glucose) levels go over 100 mg/dL.
    • It helps:
      • Move glucose into muscle and fat cells so they can use it for energy.
      • Store glucose in the liver and muscles as glycogen.
      • Turn extra glucose into fatty acids, which are a type of fat.
  2. What Glucagon Does:

    • Glucagon is released by different cells in the pancreas when blood sugar levels drop below 70 mg/dL.
    • It helps:
      • Break down glycogen in the liver and muscles to release glucose back into the blood.
      • Create glucose in the liver from things that are not carbohydrates, like proteins.
      • Break down fat in fat cells, releasing fatty acids for energy.

These two hormones work against each other to keep blood sugar levels between 70 and 130 mg/dL. This balance is important for our body to function properly.

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How Do Insulin and Glucagon Orchestrate Energy Homeostasis?

Insulin and glucagon are two important hormones that help keep our energy levels balanced.

  1. What Insulin Does:

    • Insulin is made by special cells in the pancreas when blood sugar (glucose) levels go over 100 mg/dL.
    • It helps:
      • Move glucose into muscle and fat cells so they can use it for energy.
      • Store glucose in the liver and muscles as glycogen.
      • Turn extra glucose into fatty acids, which are a type of fat.
  2. What Glucagon Does:

    • Glucagon is released by different cells in the pancreas when blood sugar levels drop below 70 mg/dL.
    • It helps:
      • Break down glycogen in the liver and muscles to release glucose back into the blood.
      • Create glucose in the liver from things that are not carbohydrates, like proteins.
      • Break down fat in fat cells, releasing fatty acids for energy.

These two hormones work against each other to keep blood sugar levels between 70 and 130 mg/dL. This balance is important for our body to function properly.

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