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How Have Mendelian Principles Been Applied to Understand Human Genetic Diseases?

Mendelian principles have played a big role in helping us understand human genetic diseases. They help us figure out how traits and diseases are passed down from parents to kids.

Here are some important Mendelian ideas:

  1. Dominant and Recessive Traits: Some diseases are caused by dominant traits. For example, in Huntington's disease, just one copy of the faulty gene can cause the problem. Other diseases, like cystic fibrosis, are recessive. That means a person needs two copies of the faulty gene to have the disease.

  2. Punnett Squares: These handy charts show the chances of what traits kids might inherit. For example, if both parents carry the cystic fibrosis gene (called Ff), there is a 25% chance their child will have cystic fibrosis (ff).

  3. Pedigree Analysis: This is like drawing a family tree to see how traits are passed down. If a family tree shows many cases of hemophilia, it can reveal that it is passed down in a specific way linked to the X chromosome.

By using these Mendelian ideas, scientists can better predict diseases, offer genetic advice, and create treatments that target specific conditions!

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How Have Mendelian Principles Been Applied to Understand Human Genetic Diseases?

Mendelian principles have played a big role in helping us understand human genetic diseases. They help us figure out how traits and diseases are passed down from parents to kids.

Here are some important Mendelian ideas:

  1. Dominant and Recessive Traits: Some diseases are caused by dominant traits. For example, in Huntington's disease, just one copy of the faulty gene can cause the problem. Other diseases, like cystic fibrosis, are recessive. That means a person needs two copies of the faulty gene to have the disease.

  2. Punnett Squares: These handy charts show the chances of what traits kids might inherit. For example, if both parents carry the cystic fibrosis gene (called Ff), there is a 25% chance their child will have cystic fibrosis (ff).

  3. Pedigree Analysis: This is like drawing a family tree to see how traits are passed down. If a family tree shows many cases of hemophilia, it can reveal that it is passed down in a specific way linked to the X chromosome.

By using these Mendelian ideas, scientists can better predict diseases, offer genetic advice, and create treatments that target specific conditions!

Related articles