Checkpoints are important for keeping the cell cycle running smoothly, but they aren’t perfect. Here are some of their limitations and possible fixes:

• G1 Checkpoint: This checkpoint checks if the DNA is healthy. If the DNA is damaged, the cell might keep dividing, which can lead to mistakes.

  • Solution: We could improve the way cells fix their DNA to get better results.

• G2 Checkpoint: This checkpoint makes sure all the DNA has been copied correctly. If it misses problems, it could cause issues with the number of genes.

  • Solution: Creating drugs that help this checkpoint work better might be a good idea.

• M Checkpoint: This checkpoint looks at whether chromosomes are lined up properly. If they aren’t, it could cause the wrong number of chromosomes.

  • Solution: Studying the proteins that help in lining up these chromosomes could help us find ways to avoid mistakes.

In summary, while checkpoints act like a safety net, their flaws remind us that we need to keep making scientific progress.