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In What Ways Do Mutations in the Cell Division Process Trigger Tumorigenesis?

Mutations in how cells divide can lead to the formation of tumors in a few important ways:

  1. Oncogenes Activation: Sometimes, mutations change normal genes called proto-oncogenes into harmful ones called oncogenes. This makes the cells divide without stopping. It’s like having a stuck “go” button, causing cells to multiply too fast.

  2. Tumor Suppressor Genes: There are also genes that help keep cell growth in check, known as tumor suppressor genes. When mutations turn off these genes (like p53), it’s like removing the brakes on a car. Without these brakes, the messed-up cells keep dividing.

  3. Genome Instability: Mutations can create problems when DNA is copied or repaired. This leads to more mistakes in the genetic material. Over time, these extra errors can help cancer develop.

In simple terms, it's like a mix of errors that can lead to tumors!

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In What Ways Do Mutations in the Cell Division Process Trigger Tumorigenesis?

Mutations in how cells divide can lead to the formation of tumors in a few important ways:

  1. Oncogenes Activation: Sometimes, mutations change normal genes called proto-oncogenes into harmful ones called oncogenes. This makes the cells divide without stopping. It’s like having a stuck “go” button, causing cells to multiply too fast.

  2. Tumor Suppressor Genes: There are also genes that help keep cell growth in check, known as tumor suppressor genes. When mutations turn off these genes (like p53), it’s like removing the brakes on a car. Without these brakes, the messed-up cells keep dividing.

  3. Genome Instability: Mutations can create problems when DNA is copied or repaired. This leads to more mistakes in the genetic material. Over time, these extra errors can help cancer develop.

In simple terms, it's like a mix of errors that can lead to tumors!

Related articles