Genetic disorders are health problems that happen because of changes in a person's DNA. These issues can come from different sources, and we can sort them into three main groups:
Single-Gene Mutations: These are also called monogenic disorders. They happen when there is a change in just one gene. For example, cystic fibrosis is a condition that affects about 1 in 2,500 babies born in the U.S. This disorder is caused by changes in a gene called CFTR.
Chromosomal Abnormalities: This group includes disorders caused by changes to chromosomes, which are structures in our cells that hold our DNA. Down syndrome is an example, and it happens when there is an extra copy of chromosome 21. This condition occurs in about 1 in 700 births.
Multifactorial Disorders: These are caused by a mix of genetic factors and things from the environment. Conditions like heart disease and diabetes can be influenced by our genes and how we live. Studies show that about 50% of people may have genes that make them more likely to develop these conditions.
It’s important to understand these disorders. This knowledge helps with diagnosis, treatment, and possible gene therapy options. Overall, it can improve the lives of those affected by these conditions.
Genetic disorders are health problems that happen because of changes in a person's DNA. These issues can come from different sources, and we can sort them into three main groups:
Single-Gene Mutations: These are also called monogenic disorders. They happen when there is a change in just one gene. For example, cystic fibrosis is a condition that affects about 1 in 2,500 babies born in the U.S. This disorder is caused by changes in a gene called CFTR.
Chromosomal Abnormalities: This group includes disorders caused by changes to chromosomes, which are structures in our cells that hold our DNA. Down syndrome is an example, and it happens when there is an extra copy of chromosome 21. This condition occurs in about 1 in 700 births.
Multifactorial Disorders: These are caused by a mix of genetic factors and things from the environment. Conditions like heart disease and diabetes can be influenced by our genes and how we live. Studies show that about 50% of people may have genes that make them more likely to develop these conditions.
It’s important to understand these disorders. This knowledge helps with diagnosis, treatment, and possible gene therapy options. Overall, it can improve the lives of those affected by these conditions.