RNA problems are a big part of how cancer develops. This makes treating cancer more complicated in several ways:
Changes in Gene Activity: When RNA doesn't work right, it can make certain genes, called oncogenes, too active or turn off others that usually help stop cancer, called tumor suppressor genes. This messes up the normal signals in our cells. Because of this, cells can grow too much and ignore the signals that usually tell them to die.
Complicated Processes: RNA works in many different ways, like altering messenger RNA (mRNA), changing it, and interacting with types of RNA that don’t code for proteins. All these interactions make it hard to understand how tumors grow and behave.
Challenges in Treatment: Finding ways to specifically target RNA is tough. Some current treatment methods, like RNA interference and antisense therapies, have problems. They might not only attack the bad RNA but could also harm healthy cells, leading to unwanted side effects.
To tackle these problems, researchers are working on better treatments that focus on RNA and personalized medicine. They want to create advanced ways to deliver these treatments and find specific RNA targets that can be attacked without causing harm to other parts of the body. However, understanding all the complex ways RNA misregulation happens in cancer is still a major challenge. This makes finding effective cancer treatments even harder.
RNA problems are a big part of how cancer develops. This makes treating cancer more complicated in several ways:
Changes in Gene Activity: When RNA doesn't work right, it can make certain genes, called oncogenes, too active or turn off others that usually help stop cancer, called tumor suppressor genes. This messes up the normal signals in our cells. Because of this, cells can grow too much and ignore the signals that usually tell them to die.
Complicated Processes: RNA works in many different ways, like altering messenger RNA (mRNA), changing it, and interacting with types of RNA that don’t code for proteins. All these interactions make it hard to understand how tumors grow and behave.
Challenges in Treatment: Finding ways to specifically target RNA is tough. Some current treatment methods, like RNA interference and antisense therapies, have problems. They might not only attack the bad RNA but could also harm healthy cells, leading to unwanted side effects.
To tackle these problems, researchers are working on better treatments that focus on RNA and personalized medicine. They want to create advanced ways to deliver these treatments and find specific RNA targets that can be attacked without causing harm to other parts of the body. However, understanding all the complex ways RNA misregulation happens in cancer is still a major challenge. This makes finding effective cancer treatments even harder.