The way drugs are made can really affect how they are given to people. This can create some challenges:

1. Formulation Issues: Some drug formulas just don't work well with every method of giving them. This can make them less effective.

2. Absorption Differences: When you take medicine by mouth, it might not always be absorbed the same way. Sometimes, food or different stomach conditions can affect how well the body takes in the medicine.

3. Invasive Methods: Giving medicine through needles (like IVs or shots) needs trained people to do it. It can also be uncomfortable for the patient.

4. Keeping Up with Medicine: If the way to take the medicine is complicated or unpleasant, people might not stick to their treatment, especially if they have to take it for a long time.

Solutions:

• Making better drug formulas that work well with the preferred ways to take them can help solve some of these problems.
• Creating easier-to-use devices, like auto-injectors, can make it simpler to give the medicine and reduce some of the challenges.