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What Role Do Genetic Factors Play in the Development of Multiple Sclerosis?

Genetic factors play a big role in how Multiple Sclerosis (MS) develops.

Here are some important points to understand:

  • Increased Risk: If someone has a close family member, like a parent or sibling, with MS, their chance of getting it is about 2-3%. This is much higher than the general risk of just 0.1% for most people.

  • Genetic Differences: Researchers have found over 200 different gene changes that can make someone more likely to get MS. These changes mostly affect how the immune system works.

  • HLA Gene Connection: One important gene, called HLA-DRB1, can raise the risk of getting MS by 3 to 4 times. This shows just how important this gene is in the development of MS.

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What Role Do Genetic Factors Play in the Development of Multiple Sclerosis?

Genetic factors play a big role in how Multiple Sclerosis (MS) develops.

Here are some important points to understand:

  • Increased Risk: If someone has a close family member, like a parent or sibling, with MS, their chance of getting it is about 2-3%. This is much higher than the general risk of just 0.1% for most people.

  • Genetic Differences: Researchers have found over 200 different gene changes that can make someone more likely to get MS. These changes mostly affect how the immune system works.

  • HLA Gene Connection: One important gene, called HLA-DRB1, can raise the risk of getting MS by 3 to 4 times. This shows just how important this gene is in the development of MS.

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