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What Role Do Oncogenes and Tumor Suppressor Genes Play in Neoplasia?

Oncogenes and tumor suppressor genes are important for understanding cancer:

  • Oncogenes: These are altered versions of normal genes that push cells to grow and multiply. You can think of them like a "gas pedal" that makes cells start racing ahead without stopping.

  • Tumor Suppressor Genes: These work like the "brakes." They normally help control how fast cells divide and can stop tumors from forming. When these genes are changed or not working properly, the brakes are off, and cell growth can go out of control.

When oncogenes and tumor suppressor genes are balanced, things are okay. But when they aren't, it can lead to cancer.

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General Pathology for Medical PathologySystems Pathology for Medical PathologyNeoplastic Pathology for Medical Pathology
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What Role Do Oncogenes and Tumor Suppressor Genes Play in Neoplasia?

Oncogenes and tumor suppressor genes are important for understanding cancer:

  • Oncogenes: These are altered versions of normal genes that push cells to grow and multiply. You can think of them like a "gas pedal" that makes cells start racing ahead without stopping.

  • Tumor Suppressor Genes: These work like the "brakes." They normally help control how fast cells divide and can stop tumors from forming. When these genes are changed or not working properly, the brakes are off, and cell growth can go out of control.

When oncogenes and tumor suppressor genes are balanced, things are okay. But when they aren't, it can lead to cancer.

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