Neuroinflammation is really important when we talk about Parkinson's disease (PD). Here are some key points to help understand it better:
Microglial Activation: In Parkinson's disease, special cells called microglia become too active. When this happens, they release substances that cause inflammation. Unfortunately, this can harm brain cells.
Cellular Stress: When inflammation increases, it also causes oxidative stress. This makes brain cells more likely to get damaged and die.
Alpha-Synuclein: A protein called alpha-synuclein builds up in the brains of people with Parkinson's. Neuroinflammation might make this buildup worse, which can create a harmful cycle of damage.
Neuroprotection vs. Neurotoxicity: At first, inflammation might help protect the brain. But if it stays active for too long, it can actually become toxic and harm the brain.
Understanding neuroinflammation is really important. It could help us find new ways to treat Parkinson's disease, slow down how it progresses, and ease some of the symptoms.
Neuroinflammation is really important when we talk about Parkinson's disease (PD). Here are some key points to help understand it better:
Microglial Activation: In Parkinson's disease, special cells called microglia become too active. When this happens, they release substances that cause inflammation. Unfortunately, this can harm brain cells.
Cellular Stress: When inflammation increases, it also causes oxidative stress. This makes brain cells more likely to get damaged and die.
Alpha-Synuclein: A protein called alpha-synuclein builds up in the brains of people with Parkinson's. Neuroinflammation might make this buildup worse, which can create a harmful cycle of damage.
Neuroprotection vs. Neurotoxicity: At first, inflammation might help protect the brain. But if it stays active for too long, it can actually become toxic and harm the brain.
Understanding neuroinflammation is really important. It could help us find new ways to treat Parkinson's disease, slow down how it progresses, and ease some of the symptoms.