Neuroinflammation is an important part of understanding Major Depressive Disorder, or MDD. Studies show that about 30-50% of people with MDD have higher levels of certain substances that indicate inflammation, called inflammatory markers.
Here are some key points to know:
People with depression often have increased amounts of pro-inflammatory cytokines, like IL-1, IL-6, and TNF-α, linked to their depressive feelings.
Research shows that individuals with depression have C-reactive protein (CRP) levels that are 2.5 times higher than those without depression.
Studies with animals show that when they are given cytokines, they can start to act like they are depressed.
These findings suggest that neuroinflammation may mess with systems in the brain that help with mood, learning, and recovery. This can lead to the start and continuation of MDD.
Understanding how neuroinflammation is connected to depression can help researchers create new treatments that reduce inflammation to help those who are depressed.
Neuroinflammation is an important part of understanding Major Depressive Disorder, or MDD. Studies show that about 30-50% of people with MDD have higher levels of certain substances that indicate inflammation, called inflammatory markers.
Here are some key points to know:
People with depression often have increased amounts of pro-inflammatory cytokines, like IL-1, IL-6, and TNF-α, linked to their depressive feelings.
Research shows that individuals with depression have C-reactive protein (CRP) levels that are 2.5 times higher than those without depression.
Studies with animals show that when they are given cytokines, they can start to act like they are depressed.
These findings suggest that neuroinflammation may mess with systems in the brain that help with mood, learning, and recovery. This can lead to the start and continuation of MDD.
Understanding how neuroinflammation is connected to depression can help researchers create new treatments that reduce inflammation to help those who are depressed.